Evidence claim

Boltz-2: description

Description of Boltz-2

Boltz-2 predicts biomolecular complex structures and binding affinity.

Replace a placeholder description with a sourced functional description (issue #88). Historical releases retain the original value.

Evidence

Source checking verifies the cited claim or transcription. It does not establish independent reproduction.

Evidence table

Inspect claims, sources and review details

Trace each statement to its source and review. A context-only reference supports the record generally; it does not verify an individual field. Source checking does not reproduce an experiment.

One row per statement and cited source. Multiple citations are not independent evaluations. Shared locators are labelled explicitly.

49 evidence rows matching the loaded filters

Claims, original sources and review scope · Release 2026-10-23-5347695500ed
Property and statement	Original source and location	Review and provenance
Claimed field description Context-only references	Boltz-2 official resource Original source ↗ Reviewed profile summary (2026-09-23): evidence-official-f780521ccebbb0691f9e, evidence-official-5a9e55abdf288d9dd8da, evidence-official-39a15ed8072aeea14a22, evidence-official-734117ed8501eb26fefc, evidence-official-7cb8cb7f091536b92c11, evidence-official-bd6ec1f819e22f075c32: src/boltz/model/models/boltz2.py: Boltz2.__init__, forward, PairformerModule, AtomDiffusion and AffinityModule; docs/prediction.md: affinity outputs; Boltz-2 report Sections 2 Data, 3 Architecture, 4 Training and 6 Limitations Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: Not recorded Retrieved: 2026-09-16T10:50:02Z	not individually reviewed No individual claim review recorded Audit details Field: `attributes.field` Source artifact SHA-256: `Not recorded` Hash scope: Hash scope not separately documented; inspect source record
Claimed field description Context-only references	jwohlwend/boltz: docs/training.md Original source ↗ Reviewed profile summary (2026-09-23): evidence-official-f780521ccebbb0691f9e, evidence-official-5a9e55abdf288d9dd8da, evidence-official-39a15ed8072aeea14a22, evidence-official-734117ed8501eb26fefc, evidence-official-7cb8cb7f091536b92c11, evidence-official-bd6ec1f819e22f075c32: src/boltz/model/models/boltz2.py: Boltz2.__init__, forward, PairformerModule, AtomDiffusion and AffinityModule; docs/prediction.md: affinity outputs; Boltz-2 report Sections 2 Data, 3 Architecture, 4 Training and 6 Limitations Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: b1ebfc46ecf57f5414e0d1a6f9027bbb122c53bc Retrieved: 2026-09-16T19:46:19.465940+00:00	not individually reviewed No individual claim review recorded Audit details Field: `attributes.field` Source artifact SHA-256: `4574fa3cac9d086708dce59de68a144dc337722af3242db9adfd6798bb37e21c` Hash scope: SHA-256 of retrieved original artifact bytes Format: original_artifact Inspected artifact
Claimed field description Context-only references	jwohlwend/boltz: docs/prediction.md Original source ↗ Reviewed profile summary (2026-09-23): evidence-official-f780521ccebbb0691f9e, evidence-official-5a9e55abdf288d9dd8da, evidence-official-39a15ed8072aeea14a22, evidence-official-734117ed8501eb26fefc, evidence-official-7cb8cb7f091536b92c11, evidence-official-bd6ec1f819e22f075c32: src/boltz/model/models/boltz2.py: Boltz2.__init__, forward, PairformerModule, AtomDiffusion and AffinityModule; docs/prediction.md: affinity outputs; Boltz-2 report Sections 2 Data, 3 Architecture, 4 Training and 6 Limitations Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: b1ebfc46ecf57f5414e0d1a6f9027bbb122c53bc Retrieved: 2026-09-16T19:46:19.465940+00:00	not individually reviewed No individual claim review recorded Audit details Field: `attributes.field` Source artifact SHA-256: `b9cb2ff437389864bde02e7e9fd9fbcc7de189ca2e240a5f3fb6261ca595a795` Hash scope: SHA-256 of retrieved original artifact bytes Format: original_artifact Inspected artifact
Claimed field description Context-only references	jwohlwend/boltz: src/boltz/model/models/boltz2.py Original source ↗ Reviewed profile summary (2026-09-23): evidence-official-f780521ccebbb0691f9e, evidence-official-5a9e55abdf288d9dd8da, evidence-official-39a15ed8072aeea14a22, evidence-official-734117ed8501eb26fefc, evidence-official-7cb8cb7f091536b92c11, evidence-official-bd6ec1f819e22f075c32: src/boltz/model/models/boltz2.py: Boltz2.__init__, forward, PairformerModule, AtomDiffusion and AffinityModule; docs/prediction.md: affinity outputs; Boltz-2 report Sections 2 Data, 3 Architecture, 4 Training and 6 Limitations Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: b1ebfc46ecf57f5414e0d1a6f9027bbb122c53bc Retrieved: 2026-09-16T19:46:19.465940+00:00	not individually reviewed No individual claim review recorded Audit details Field: `attributes.field` Source artifact SHA-256: `f05169e66488910fc11c6a56b56d19a58e3f43649586218df75573eeff7a9945` Hash scope: SHA-256 of retrieved original artifact bytes Format: original_artifact Inspected artifact
Claimed field description Context-only references	jwohlwend/boltz: scripts/train/configs/full.yaml Original source ↗ Reviewed profile summary (2026-09-23): evidence-official-f780521ccebbb0691f9e, evidence-official-5a9e55abdf288d9dd8da, evidence-official-39a15ed8072aeea14a22, evidence-official-734117ed8501eb26fefc, evidence-official-7cb8cb7f091536b92c11, evidence-official-bd6ec1f819e22f075c32: src/boltz/model/models/boltz2.py: Boltz2.__init__, forward, PairformerModule, AtomDiffusion and AffinityModule; docs/prediction.md: affinity outputs; Boltz-2 report Sections 2 Data, 3 Architecture, 4 Training and 6 Limitations Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: b1ebfc46ecf57f5414e0d1a6f9027bbb122c53bc Retrieved: 2026-09-16T19:46:19.465940+00:00	not individually reviewed No individual claim review recorded Audit details Field: `attributes.field` Source artifact SHA-256: `70aa005d0c29b1c28918e104b92fd43b5cfde6157993dfcd8fe832e9a2e107dc` Hash scope: SHA-256 of retrieved original artifact bytes Format: original_artifact Inspected artifact
Claimed field description Context-only references	boltz2: Journal full-text XML Original source ↗ Reviewed profile summary (2026-09-23): evidence-official-f780521ccebbb0691f9e, evidence-official-5a9e55abdf288d9dd8da, evidence-official-39a15ed8072aeea14a22, evidence-official-734117ed8501eb26fefc, evidence-official-7cb8cb7f091536b92c11, evidence-official-bd6ec1f819e22f075c32: src/boltz/model/models/boltz2.py: Boltz2.__init__, forward, PairformerModule, AtomDiffusion and AffinityModule; docs/prediction.md: affinity outputs; Boltz-2 report Sections 2 Data, 3 Architecture, 4 Training and 6 Limitations Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: preprint; 1 Retrieved: 2026-09-16T20:20:56.438787+00:00	not individually reviewed No individual claim review recorded Audit details Field: `attributes.field` Source artifact SHA-256: `4ba7533096d594725e7f6362807aee6cc19596571fd09d9ae82fc49c6daa16fd` Hash scope: SHA-256 of retrieved original artifact bytes Format: original_artifact Inspected artifact
Claimed field description Context-only references	jwohlwend/boltz: README.md Original source ↗ Reviewed profile summary (2026-09-23): evidence-official-f780521ccebbb0691f9e, evidence-official-5a9e55abdf288d9dd8da, evidence-official-39a15ed8072aeea14a22, evidence-official-734117ed8501eb26fefc, evidence-official-7cb8cb7f091536b92c11, evidence-official-bd6ec1f819e22f075c32: src/boltz/model/models/boltz2.py: Boltz2.__init__, forward, PairformerModule, AtomDiffusion and AffinityModule; docs/prediction.md: affinity outputs; Boltz-2 report Sections 2 Data, 3 Architecture, 4 Training and 6 Limitations Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: b1ebfc46ecf57f5414e0d1a6f9027bbb122c53bc Retrieved: 2026-09-16T19:46:19.465940+00:00	not individually reviewed No individual claim review recorded Audit details Field: `attributes.field` Source artifact SHA-256: `79149435313841e6f9cc0c8b581259f3952a2469cbe6f9a733f7143b557025c2` Hash scope: SHA-256 of retrieved original artifact bytes Format: original_artifact Inspected artifact
Previous value Existing candidate catalogue entry; exact checkpoint and metadata require primary-source review. Context-only references	Boltz-2 official resource Original source ↗ Reviewed profile summary (2026-09-23): evidence-official-f780521ccebbb0691f9e, evidence-official-5a9e55abdf288d9dd8da, evidence-official-39a15ed8072aeea14a22, evidence-official-734117ed8501eb26fefc, evidence-official-7cb8cb7f091536b92c11, evidence-official-bd6ec1f819e22f075c32: src/boltz/model/models/boltz2.py: Boltz2.__init__, forward, PairformerModule, AtomDiffusion and AffinityModule; docs/prediction.md: affinity outputs; Boltz-2 report Sections 2 Data, 3 Architecture, 4 Training and 6 Limitations Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: Not recorded Retrieved: 2026-09-16T10:50:02Z	not individually reviewed No individual claim review recorded Audit details Field: `attributes.previous_value` Source artifact SHA-256: `Not recorded` Hash scope: Hash scope not separately documented; inspect source record
Previous value Existing candidate catalogue entry; exact checkpoint and metadata require primary-source review. Context-only references	jwohlwend/boltz: docs/training.md Original source ↗ Reviewed profile summary (2026-09-23): evidence-official-f780521ccebbb0691f9e, evidence-official-5a9e55abdf288d9dd8da, evidence-official-39a15ed8072aeea14a22, evidence-official-734117ed8501eb26fefc, evidence-official-7cb8cb7f091536b92c11, evidence-official-bd6ec1f819e22f075c32: src/boltz/model/models/boltz2.py: Boltz2.__init__, forward, PairformerModule, AtomDiffusion and AffinityModule; docs/prediction.md: affinity outputs; Boltz-2 report Sections 2 Data, 3 Architecture, 4 Training and 6 Limitations Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: b1ebfc46ecf57f5414e0d1a6f9027bbb122c53bc Retrieved: 2026-09-16T19:46:19.465940+00:00	not individually reviewed No individual claim review recorded Audit details Field: `attributes.previous_value` Source artifact SHA-256: `4574fa3cac9d086708dce59de68a144dc337722af3242db9adfd6798bb37e21c` Hash scope: SHA-256 of retrieved original artifact bytes Format: original_artifact Inspected artifact
Previous value Existing candidate catalogue entry; exact checkpoint and metadata require primary-source review. Context-only references	jwohlwend/boltz: docs/prediction.md Original source ↗ Reviewed profile summary (2026-09-23): evidence-official-f780521ccebbb0691f9e, evidence-official-5a9e55abdf288d9dd8da, evidence-official-39a15ed8072aeea14a22, evidence-official-734117ed8501eb26fefc, evidence-official-7cb8cb7f091536b92c11, evidence-official-bd6ec1f819e22f075c32: src/boltz/model/models/boltz2.py: Boltz2.__init__, forward, PairformerModule, AtomDiffusion and AffinityModule; docs/prediction.md: affinity outputs; Boltz-2 report Sections 2 Data, 3 Architecture, 4 Training and 6 Limitations Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: b1ebfc46ecf57f5414e0d1a6f9027bbb122c53bc Retrieved: 2026-09-16T19:46:19.465940+00:00	not individually reviewed No individual claim review recorded Audit details Field: `attributes.previous_value` Source artifact SHA-256: `b9cb2ff437389864bde02e7e9fd9fbcc7de189ca2e240a5f3fb6261ca595a795` Hash scope: SHA-256 of retrieved original artifact bytes Format: original_artifact Inspected artifact

How to read the evidence

Sources and history

Release 2026-10-23-5347695500ed · Record review: source checked

7 source records and release history

Boltz-2 official resource · Original source · Not reported
jwohlwend/boltz: README.md · Original source · b1ebfc46ecf57f5414e0d1a6f9027bbb122c53bc
jwohlwend/boltz: docs/prediction.md · Original source · b1ebfc46ecf57f5414e0d1a6f9027bbb122c53bc
jwohlwend/boltz: docs/training.md · Original source · b1ebfc46ecf57f5414e0d1a6f9027bbb122c53bc
jwohlwend/boltz: src/boltz/model/models/boltz2.py · Original source · b1ebfc46ecf57f5414e0d1a6f9027bbb122c53bc
jwohlwend/boltz: scripts/train/configs/full.yaml · Original source · b1ebfc46ecf57f5414e0d1a6f9027bbb122c53bc
boltz2: Journal full-text XML · Original source · preprint; 1

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Technical metadata and extraction receipts

Stable ID: metadata-correction-792fd87b2c331837fae5

areas: molecular-interactions
method types: foundation_model
field: description
previous value: Existing candidate catalogue entry; exact checkpoint and metadata require primary-source review.
value: Boltz-2 predicts biomolecular complex structures and binding affinity.
source locator: Reviewed profile summary (2026-09-23): evidence-official-f780521ccebbb0691f9e, evidence-official-5a9e55abdf288d9dd8da, evidence-official-39a15ed8072aeea14a22, evidence-official-734117ed8501eb26fefc, evidence-official-7cb8cb7f091536b92c11, evidence-official-bd6ec1f819e22f075c32: src/boltz/model/models/boltz2.py: Boltz2.__init__, forward, PairformerModule, AtomDiffusion and AffinityModule; docs/prediction.md: affinity outputs; Boltz-2 report Sections 2 Data, 3 Architecture, 4 Training and 6 Limitations
review: method: automated-source-review; ai-assisted-source-review; reviewer: claude; reviewer note: Extractor: Claude integrator agent for issue #88. Reviewer: a separate Claude review agent, independent of the extractor; no human review claimed.; date: 2026-10-11; method note: Compared the store diff with origin/main, read each new description against its cited source passage and checked the licence of each new source record.; note: Approved. Checked the new sources' licences against the arXiv abstract pages and Europe PMC, the 7 scFoundation pipeline descriptions against their abstracts, the language-model descriptions against their model cards and reports, and the TAPE architecture figures against the TAPE paper; all correct. The catalogue entries reuse reviewed profile summaries.; receipt: data/omics/qa-descriptions-20261011-b/review.json

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subject: Boltz-2

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