rewirebio.iobenchmarks
Evidence claim

ProtGPT2: description

Description of ProtGPT2

Deep unsupervised language model trained on protein sequences that generates de novo protein sequences, scored in ProteinGym as a zero-shot single-sequence substitution baseline.

Replace a placeholder or provenance description with a sourced functional description (issue #88a). Historical releases retain the original value.

Evidence

Source checking verifies the cited claim or transcription. It does not establish independent reproduction.

Evidence table

Inspect claims, sources and review details

Trace each statement to its source and review. A context-only reference supports the record generally; it does not verify an individual field. Source checking does not reproduce an experiment.

One row per statement and cited source. Multiple citations are not independent evaluations. Shared locators are labelled explicitly.

21 evidence rows matching the loaded filters

Claims, original sources and review scope · Release 2026-10-22-1b7cf027e4f6
Property and statementOriginal source and locationReview and provenance
Claimed field
description
Context-only references
Abstract: ProtGPT2 is a deep unsupervised language model for protein design

Original source ↗

uc20260930-source-proteingym-amfr-spearman: Benchmark CSV header (model scored in the zero-shot DMS substitution benchmark); run-doc-proteingym-readme-md-144fe22b: README 'Leaderboard' baseline table (model name, input modalities, reference); qa-descriptions-20261010-source-protgpt2: abstract

Shared locator for this statement’s cited sources; not a separate locator for each citation.

Version: Europe PMC core record MED/35896542 (title and abstract), Nature communications 2022
Retrieved: 2026-10-10T06:44:11Z

not individually reviewed

No individual claim review recorded

Audit details

Field: attributes.field

Source artifact SHA-256: 90fccf89e2600cc576108d6a6ded86f9577c4a20dae8a60b06b35c7ba8dc287f

Hash scope: SHA-256 of one retrieval of a Europe PMC REST search response. The response is not byte-stable: on 2026-10-10 a second retrieval of 10 of these 31 records differed only in JSON key order and parsed to identical content. The title and abstractText fields are the evidence.

Inspected artifact

Claimed field
description
Context-only references
OATML-Markslab/ProteinGym / README.md

Original source ↗

uc20260930-source-proteingym-amfr-spearman: Benchmark CSV header (model scored in the zero-shot DMS substitution benchmark); run-doc-proteingym-readme-md-144fe22b: README 'Leaderboard' baseline table (model name, input modalities, reference); qa-descriptions-20261010-source-protgpt2: abstract

Shared locator for this statement’s cited sources; not a separate locator for each citation.

Version: Git commit 144fe22b07dfaeec2b366f2346203a9838a55b4c
Retrieved: 2026-09-17T09:32:03.517591+00:00

not individually reviewed

No individual claim review recorded

Audit details

Field: attributes.field

Source artifact SHA-256: 321487a8de52c6cfa647a658f61150dd72e0acb0125470524fb94d1f8b23321a

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Claimed field
description
Context-only references
ProteinGym AMFR assay-level Spearman comparison

Original source ↗

uc20260930-source-proteingym-amfr-spearman: Benchmark CSV header (model scored in the zero-shot DMS substitution benchmark); run-doc-proteingym-readme-md-144fe22b: README 'Leaderboard' baseline table (model name, input modalities, reference); qa-descriptions-20261010-source-protgpt2: abstract

Shared locator for this statement’s cited sources; not a separate locator for each citation.

Version: 144fe22b07dfaeec2b366f2346203a9838a55b4c
Retrieved: 2026-09-30

not individually reviewed

No individual claim review recorded

Audit details

Field: attributes.field

Source artifact SHA-256: f432423b87f79ac9778dfac86e3d95be041d246bc618dc0a406b35b0b7466437

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Previous value
Named prediction model family identified in the cited primary source. Exact fitted configurations and scores are separate records.
Context-only references
Abstract: ProtGPT2 is a deep unsupervised language model for protein design

Original source ↗

uc20260930-source-proteingym-amfr-spearman: Benchmark CSV header (model scored in the zero-shot DMS substitution benchmark); run-doc-proteingym-readme-md-144fe22b: README 'Leaderboard' baseline table (model name, input modalities, reference); qa-descriptions-20261010-source-protgpt2: abstract

Shared locator for this statement’s cited sources; not a separate locator for each citation.

Version: Europe PMC core record MED/35896542 (title and abstract), Nature communications 2022
Retrieved: 2026-10-10T06:44:11Z

not individually reviewed

No individual claim review recorded

Audit details

Field: attributes.previous_value

Source artifact SHA-256: 90fccf89e2600cc576108d6a6ded86f9577c4a20dae8a60b06b35c7ba8dc287f

Hash scope: SHA-256 of one retrieval of a Europe PMC REST search response. The response is not byte-stable: on 2026-10-10 a second retrieval of 10 of these 31 records differed only in JSON key order and parsed to identical content. The title and abstractText fields are the evidence.

Inspected artifact

Previous value
Named prediction model family identified in the cited primary source. Exact fitted configurations and scores are separate records.
Context-only references
OATML-Markslab/ProteinGym / README.md

Original source ↗

uc20260930-source-proteingym-amfr-spearman: Benchmark CSV header (model scored in the zero-shot DMS substitution benchmark); run-doc-proteingym-readme-md-144fe22b: README 'Leaderboard' baseline table (model name, input modalities, reference); qa-descriptions-20261010-source-protgpt2: abstract

Shared locator for this statement’s cited sources; not a separate locator for each citation.

Version: Git commit 144fe22b07dfaeec2b366f2346203a9838a55b4c
Retrieved: 2026-09-17T09:32:03.517591+00:00

not individually reviewed

No individual claim review recorded

Audit details

Field: attributes.previous_value

Source artifact SHA-256: 321487a8de52c6cfa647a658f61150dd72e0acb0125470524fb94d1f8b23321a

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Previous value
Named prediction model family identified in the cited primary source. Exact fitted configurations and scores are separate records.
Context-only references
ProteinGym AMFR assay-level Spearman comparison

Original source ↗

uc20260930-source-proteingym-amfr-spearman: Benchmark CSV header (model scored in the zero-shot DMS substitution benchmark); run-doc-proteingym-readme-md-144fe22b: README 'Leaderboard' baseline table (model name, input modalities, reference); qa-descriptions-20261010-source-protgpt2: abstract

Shared locator for this statement’s cited sources; not a separate locator for each citation.

Version: 144fe22b07dfaeec2b366f2346203a9838a55b4c
Retrieved: 2026-09-30

not individually reviewed

No individual claim review recorded

Audit details

Field: attributes.previous_value

Source artifact SHA-256: f432423b87f79ac9778dfac86e3d95be041d246bc618dc0a406b35b0b7466437

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Source location
uc20260930-source-proteingym-amfr-spearman: Benchmark CSV header (model scored in the zero-shot DMS substitution benchmark); run-doc-proteingym-readme-md-144fe22b: README 'Leaderboard' baseline table (model name, input modalities, reference); qa-descriptions-20261010-source-protgpt2: abstract
Context-only references
Abstract: ProtGPT2 is a deep unsupervised language model for protein design

Original source ↗

uc20260930-source-proteingym-amfr-spearman: Benchmark CSV header (model scored in the zero-shot DMS substitution benchmark); run-doc-proteingym-readme-md-144fe22b: README 'Leaderboard' baseline table (model name, input modalities, reference); qa-descriptions-20261010-source-protgpt2: abstract

Shared locator for this statement’s cited sources; not a separate locator for each citation.

Version: Europe PMC core record MED/35896542 (title and abstract), Nature communications 2022
Retrieved: 2026-10-10T06:44:11Z

not individually reviewed

No individual claim review recorded

Audit details

Field: attributes.source_locator

Source artifact SHA-256: 90fccf89e2600cc576108d6a6ded86f9577c4a20dae8a60b06b35c7ba8dc287f

Hash scope: SHA-256 of one retrieval of a Europe PMC REST search response. The response is not byte-stable: on 2026-10-10 a second retrieval of 10 of these 31 records differed only in JSON key order and parsed to identical content. The title and abstractText fields are the evidence.

Inspected artifact

Source location
uc20260930-source-proteingym-amfr-spearman: Benchmark CSV header (model scored in the zero-shot DMS substitution benchmark); run-doc-proteingym-readme-md-144fe22b: README 'Leaderboard' baseline table (model name, input modalities, reference); qa-descriptions-20261010-source-protgpt2: abstract
Context-only references
OATML-Markslab/ProteinGym / README.md

Original source ↗

uc20260930-source-proteingym-amfr-spearman: Benchmark CSV header (model scored in the zero-shot DMS substitution benchmark); run-doc-proteingym-readme-md-144fe22b: README 'Leaderboard' baseline table (model name, input modalities, reference); qa-descriptions-20261010-source-protgpt2: abstract

Shared locator for this statement’s cited sources; not a separate locator for each citation.

Version: Git commit 144fe22b07dfaeec2b366f2346203a9838a55b4c
Retrieved: 2026-09-17T09:32:03.517591+00:00

not individually reviewed

No individual claim review recorded

Audit details

Field: attributes.source_locator

Source artifact SHA-256: 321487a8de52c6cfa647a658f61150dd72e0acb0125470524fb94d1f8b23321a

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Source location
uc20260930-source-proteingym-amfr-spearman: Benchmark CSV header (model scored in the zero-shot DMS substitution benchmark); run-doc-proteingym-readme-md-144fe22b: README 'Leaderboard' baseline table (model name, input modalities, reference); qa-descriptions-20261010-source-protgpt2: abstract
Context-only references
ProteinGym AMFR assay-level Spearman comparison

Original source ↗

uc20260930-source-proteingym-amfr-spearman: Benchmark CSV header (model scored in the zero-shot DMS substitution benchmark); run-doc-proteingym-readme-md-144fe22b: README 'Leaderboard' baseline table (model name, input modalities, reference); qa-descriptions-20261010-source-protgpt2: abstract

Shared locator for this statement’s cited sources; not a separate locator for each citation.

Version: 144fe22b07dfaeec2b366f2346203a9838a55b4c
Retrieved: 2026-09-30

not individually reviewed

No individual claim review recorded

Audit details

Field: attributes.source_locator

Source artifact SHA-256: f432423b87f79ac9778dfac86e3d95be041d246bc618dc0a406b35b0b7466437

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Claimed value
Deep unsupervised language model trained on protein sequences that generates de novo protein sequences, scored in ProteinGym as a zero-shot single-sequence substitution baseline.
Context-only references
Abstract: ProtGPT2 is a deep unsupervised language model for protein design

Original source ↗

uc20260930-source-proteingym-amfr-spearman: Benchmark CSV header (model scored in the zero-shot DMS substitution benchmark); run-doc-proteingym-readme-md-144fe22b: README 'Leaderboard' baseline table (model name, input modalities, reference); qa-descriptions-20261010-source-protgpt2: abstract

Shared locator for this statement’s cited sources; not a separate locator for each citation.

Version: Europe PMC core record MED/35896542 (title and abstract), Nature communications 2022
Retrieved: 2026-10-10T06:44:11Z

not individually reviewed

No individual claim review recorded

Audit details

Field: attributes.value

Source artifact SHA-256: 90fccf89e2600cc576108d6a6ded86f9577c4a20dae8a60b06b35c7ba8dc287f

Hash scope: SHA-256 of one retrieval of a Europe PMC REST search response. The response is not byte-stable: on 2026-10-10 a second retrieval of 10 of these 31 records differed only in JSON key order and parsed to identical content. The title and abstractText fields are the evidence.

Inspected artifact

How to read the evidence

Sources and history

Release 2026-10-22-1b7cf027e4f6 · Record review: source checked

3 source records and release historyDownload this release (gzip)
Technical metadata and extraction receipts

Stable ID: metadata-correction-46d0b40f1618a5ccbf55

areas
proteins-complexes
field
description
previous value
Named prediction model family identified in the cited primary source. Exact fitted configurations and scores are separate records.
value
Deep unsupervised language model trained on protein sequences that generates de novo protein sequences, scored in ProteinGym as a zero-shot single-sequence substitution baseline.
source locator
uc20260930-source-proteingym-amfr-spearman: Benchmark CSV header (model scored in the zero-shot DMS substitution benchmark); run-doc-proteingym-readme-md-144fe22b: README 'Leaderboard' baseline table (model name, input modalities, reference); qa-descriptions-20261010-source-protgpt2: abstract
review
method: automated-source-review; ai-assisted-source-review; reviewer: claude; reviewer note: Extractor: Claude research agent for issue #88a. Reviewer: separate Claude review agent, independent of the extractor; no human review claimed; date: 2026-10-10; method note: Compared the description with the cited source text (abstract, README row, benchmark CSV header or full-text section) of re-downloaded artifacts, and previous_value with origin/main.; note: Description written from the cited source text; provenance text was generic and is kept here as previous_value. Independent review 2026-10-10: corrected. 'Transformer language model' changed to the abstract's 'deep unsupervised language model'; the abstract cites Transformer progress as motivation but does not state ProtGPT2's architecture.
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