GERP: description
Description of GERP
Scores selective constraint position by position in a multiple alignment by maximum-likelihood evolutionary rate estimation, and defines constrained elements from runs of high-scoring positions by dynamic programming.
Replace a category-only description with a sourced functional description (issue #88). Historical releases retain the original value.
Evidence
Source checking verifies the cited claim or transcription. It does not establish independent reproduction.
Evidence table
Inspect claims, sources and review details
Trace each statement to its source and review. A context-only reference supports the record generally; it does not verify an individual field. Source checking does not reproduce an experiment.
One row per statement and cited source. Multiple citations are not independent evaluations. Shared locators are labelled explicitly.
7 evidence rows matching the loaded filters
| Property and statement | Original source and location | Review and provenance |
|---|---|---|
| Claimed field description Context-only references | Identifying a high fraction of the human genome to be under selective constraint using GERP++ qa-descriptions-20261011-d-source-gerp: Abstract Version: Europe PMC full-text XML for PMC2996323, PLoS Computational Biology 2010 | not individually reviewed No individual claim review recorded Audit detailsField: Source artifact SHA-256: Hash scope: SHA-256 of one retrieval of the Europe PMC full-text XML. These renderings are not always byte-stable; the article text is the evidence. |
| Previous value Conservation or selection score used as a predictor. Context-only references | Identifying a high fraction of the human genome to be under selective constraint using GERP++ qa-descriptions-20261011-d-source-gerp: Abstract Version: Europe PMC full-text XML for PMC2996323, PLoS Computational Biology 2010 | not individually reviewed No individual claim review recorded Audit detailsField: Source artifact SHA-256: Hash scope: SHA-256 of one retrieval of the Europe PMC full-text XML. These renderings are not always byte-stable; the article text is the evidence. |
| Source location qa-descriptions-20261011-d-source-gerp: Abstract Context-only references | Identifying a high fraction of the human genome to be under selective constraint using GERP++ qa-descriptions-20261011-d-source-gerp: Abstract Version: Europe PMC full-text XML for PMC2996323, PLoS Computational Biology 2010 | not individually reviewed No individual claim review recorded Audit detailsField: Source artifact SHA-256: Hash scope: SHA-256 of one retrieval of the Europe PMC full-text XML. These renderings are not always byte-stable; the article text is the evidence. |
| Claimed value Scores selective constraint position by position in a multiple alignment by maximum-likelihood evolutionary rate estimation, and defines constrained elements from runs of high-scoring positions by dynamic programming. Context-only references | Identifying a high fraction of the human genome to be under selective constraint using GERP++ qa-descriptions-20261011-d-source-gerp: Abstract Version: Europe PMC full-text XML for PMC2996323, PLoS Computational Biology 2010 | not individually reviewed No individual claim review recorded Audit detailsField: Source artifact SHA-256: Hash scope: SHA-256 of one retrieval of the Europe PMC full-text XML. These renderings are not always byte-stable; the article text is the evidence. |
| Description Replace a category-only description with a sourced functional description (issue #88). Historical releases retain the original value. Context-only references | Identifying a high fraction of the human genome to be under selective constraint using GERP++ qa-descriptions-20261011-d-source-gerp: Abstract Version: Europe PMC full-text XML for PMC2996323, PLoS Computational Biology 2010 | not individually reviewed No individual claim review recorded Audit detailsField: Source artifact SHA-256: Hash scope: SHA-256 of one retrieval of the Europe PMC full-text XML. These renderings are not always byte-stable; the article text is the evidence. |
| Relationship: subject somatic-oncogenicity-20261009-method-gerp Context-only references | Identifying a high fraction of the human genome to be under selective constraint using GERP++ qa-descriptions-20261011-d-source-gerp: Abstract Version: Europe PMC full-text XML for PMC2996323, PLoS Computational Biology 2010 | not individually reviewed No individual claim review recorded Audit detailsField: Source artifact SHA-256: Hash scope: SHA-256 of one retrieval of the Europe PMC full-text XML. These renderings are not always byte-stable; the article text is the evidence. |
| Name GERP: description Context-only references | Identifying a high fraction of the human genome to be under selective constraint using GERP++ qa-descriptions-20261011-d-source-gerp: Abstract Version: Europe PMC full-text XML for PMC2996323, PLoS Computational Biology 2010 | not individually reviewed No individual claim review recorded Audit detailsField: Source artifact SHA-256: Hash scope: SHA-256 of one retrieval of the Europe PMC full-text XML. These renderings are not always byte-stable; the article text is the evidence. |
Sources and history
Release 2026-10-22-1b7cf027e4f6 · Record review: source checked
1 source record and release history
- Identifying a high fraction of the human genome to be under selective constraint using GERP++ · Original source · Europe PMC full-text XML for PMC2996323, PLoS Computational Biology 2010
Technical metadata and extraction receipts
Stable ID: metadata-correction-3e2f6542e135a4ce4fce
- areas
- dna-genomes
- contexts
- clinical_research
- method types
- specialist
- field
- description
- previous value
- Conservation or selection score used as a predictor.
- value
- Scores selective constraint position by position in a multiple alignment by maximum-likelihood evolutionary rate estimation, and defines constrained elements from runs of high-scoring positions by dynamic programming.
- source locator
- qa-descriptions-20261011-d-source-gerp: Abstract
- review
- method: automated-source-review; ai-assisted-source-review; reviewer: claude; reviewer note: Extractor: Claude integrator agent for issue #88. Reviewer: a separate Claude review agent, independent of the extractor; no human review claimed.; date: 2026-10-11; method note: Compared the store diff with origin/main, read each new description against its cited source passage and checked the licence of each new source record.; note: Approved. Checked the 16 Pancotti-derived descriptions word for word against PMC8921618 section 2.2, ESM therm, RaSP and ELASPIC-2 against Chu 2024, ThermoMPNN against Dieckhaus 2024, and ABYSSAL and phyloP against their abstracts; all match. Licences on the new sources are supported by Europe PMC, the PMC XML and Crossref.; receipt: data/omics/qa-descriptions-20261011-d/review.json
Related records
- subject: GERP