Evidence claim

AlphaGenome: description

AlphaGenome predicts regulatory activity and variant effects from long DNA sequences, with outputs for expression, splicing, chromatin and contact maps.

Replace a placeholder description with a sourced functional description (issue #88). Historical releases retain the original value.

Evidence

Source checking verifies the cited claim or transcription. It does not establish independent reproduction.

Evidence table

Inspect claims, sources and review details

Trace each statement to its source and review. A context-only reference supports the record generally; it does not verify an individual field. Source checking does not reproduce an experiment.

One row per statement and cited source. Multiple citations are not independent evaluations. Shared locators are labelled explicitly.

28 evidence rows matching the loaded filters

Claims, original sources and review scope · Release 2026-10-23-5347695500ed
Property and statement	Original source and location	Review and provenance
Claimed field description Context-only references	AlphaGenome official resource Original source ↗ Reviewed profile summary (2026-09-16): evidence-official-578439da3f3a3a476b7f, evidence-official-56e5abfb5f12f1cd3b20, evidence-official-bc0327ef2ea6107e1773: Paper: Unifying DNA sequence-to-function model and Discussion; README.md: Model weights and licensing; Supplementary Methods: Model (p.9), ENCODE RNA-seq Data (p.3), Contact maps Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: Not recorded Retrieved: 2026-09-16T10:50:02Z	not individually reviewed No individual claim review recorded Audit details Field: `attributes.field` Source artifact SHA-256: `Not recorded` Hash scope: Hash scope not separately documented; inspect source record
Claimed field description Context-only references	alphagenome: Journal full-text XML Original source ↗ Reviewed profile summary (2026-09-16): evidence-official-578439da3f3a3a476b7f, evidence-official-56e5abfb5f12f1cd3b20, evidence-official-bc0327ef2ea6107e1773: Paper: Unifying DNA sequence-to-function model and Discussion; README.md: Model weights and licensing; Supplementary Methods: Model (p.9), ENCODE RNA-seq Data (p.3), Contact maps Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: Retrieved page snapshot; no immutable publisher revision supplied Retrieved: 2026-09-16T19:53:03.009088+00:00	not individually reviewed No individual claim review recorded Audit details Field: `attributes.field` Source artifact SHA-256: `d159b791fc6cb7b679c151727b7b05a6e5b6388b08a89b675014983d85b6df36` Hash scope: SHA-256 of retrieved original artifact bytes Format: original_artifact Inspected artifact
Claimed field description Context-only references	google-deepmind/alphagenome_research: README.md Original source ↗ Reviewed profile summary (2026-09-16): evidence-official-578439da3f3a3a476b7f, evidence-official-56e5abfb5f12f1cd3b20, evidence-official-bc0327ef2ea6107e1773: Paper: Unifying DNA sequence-to-function model and Discussion; README.md: Model weights and licensing; Supplementary Methods: Model (p.9), ENCODE RNA-seq Data (p.3), Contact maps Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: 0db53bd4352c66d1e00a049a81da373a066e6670 Retrieved: 2026-09-16T19:46:19.361780+00:00	not individually reviewed No individual claim review recorded Audit details Field: `attributes.field` Source artifact SHA-256: `c715b22c31bd4f69e9b76236de0ab6a26c96fa0f384ad56a2f9d2cb65e262681` Hash scope: SHA-256 of retrieved original artifact bytes Format: original_artifact Inspected artifact
Claimed field description Context-only references	alphagenome-supp: Publisher supplementary archive Original source ↗ Reviewed profile summary (2026-09-16): evidence-official-578439da3f3a3a476b7f, evidence-official-56e5abfb5f12f1cd3b20, evidence-official-bc0327ef2ea6107e1773: Paper: Unifying DNA sequence-to-function model and Discussion; README.md: Model weights and licensing; Supplementary Methods: Model (p.9), ENCODE RNA-seq Data (p.3), Contact maps Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: Retrieved page snapshot; no immutable publisher revision supplied Retrieved: 2026-09-16T20:43:11.978411+00:00	not individually reviewed No individual claim review recorded Audit details Field: `attributes.field` Source artifact SHA-256: `a006a3373cfdf42c41f9be7f64b883b38ea3f16be8037ea6024b5d0463f811dc` Hash scope: SHA-256 of retrieved original artifact bytes Format: original_artifact Inspected artifact
Previous value Existing candidate catalogue entry; exact checkpoint and metadata require primary-source review. Context-only references	AlphaGenome official resource Original source ↗ Reviewed profile summary (2026-09-16): evidence-official-578439da3f3a3a476b7f, evidence-official-56e5abfb5f12f1cd3b20, evidence-official-bc0327ef2ea6107e1773: Paper: Unifying DNA sequence-to-function model and Discussion; README.md: Model weights and licensing; Supplementary Methods: Model (p.9), ENCODE RNA-seq Data (p.3), Contact maps Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: Not recorded Retrieved: 2026-09-16T10:50:02Z	not individually reviewed No individual claim review recorded Audit details Field: `attributes.previous_value` Source artifact SHA-256: `Not recorded` Hash scope: Hash scope not separately documented; inspect source record
Previous value Existing candidate catalogue entry; exact checkpoint and metadata require primary-source review. Context-only references	alphagenome: Journal full-text XML Original source ↗ Reviewed profile summary (2026-09-16): evidence-official-578439da3f3a3a476b7f, evidence-official-56e5abfb5f12f1cd3b20, evidence-official-bc0327ef2ea6107e1773: Paper: Unifying DNA sequence-to-function model and Discussion; README.md: Model weights and licensing; Supplementary Methods: Model (p.9), ENCODE RNA-seq Data (p.3), Contact maps Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: Retrieved page snapshot; no immutable publisher revision supplied Retrieved: 2026-09-16T19:53:03.009088+00:00	not individually reviewed No individual claim review recorded Audit details Field: `attributes.previous_value` Source artifact SHA-256: `d159b791fc6cb7b679c151727b7b05a6e5b6388b08a89b675014983d85b6df36` Hash scope: SHA-256 of retrieved original artifact bytes Format: original_artifact Inspected artifact
Previous value Existing candidate catalogue entry; exact checkpoint and metadata require primary-source review. Context-only references	google-deepmind/alphagenome_research: README.md Original source ↗ Reviewed profile summary (2026-09-16): evidence-official-578439da3f3a3a476b7f, evidence-official-56e5abfb5f12f1cd3b20, evidence-official-bc0327ef2ea6107e1773: Paper: Unifying DNA sequence-to-function model and Discussion; README.md: Model weights and licensing; Supplementary Methods: Model (p.9), ENCODE RNA-seq Data (p.3), Contact maps Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: 0db53bd4352c66d1e00a049a81da373a066e6670 Retrieved: 2026-09-16T19:46:19.361780+00:00	not individually reviewed No individual claim review recorded Audit details Field: `attributes.previous_value` Source artifact SHA-256: `c715b22c31bd4f69e9b76236de0ab6a26c96fa0f384ad56a2f9d2cb65e262681` Hash scope: SHA-256 of retrieved original artifact bytes Format: original_artifact Inspected artifact
Previous value Existing candidate catalogue entry; exact checkpoint and metadata require primary-source review. Context-only references	alphagenome-supp: Publisher supplementary archive Original source ↗ Reviewed profile summary (2026-09-16): evidence-official-578439da3f3a3a476b7f, evidence-official-56e5abfb5f12f1cd3b20, evidence-official-bc0327ef2ea6107e1773: Paper: Unifying DNA sequence-to-function model and Discussion; README.md: Model weights and licensing; Supplementary Methods: Model (p.9), ENCODE RNA-seq Data (p.3), Contact maps Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: Retrieved page snapshot; no immutable publisher revision supplied Retrieved: 2026-09-16T20:43:11.978411+00:00	not individually reviewed No individual claim review recorded Audit details Field: `attributes.previous_value` Source artifact SHA-256: `a006a3373cfdf42c41f9be7f64b883b38ea3f16be8037ea6024b5d0463f811dc` Hash scope: SHA-256 of retrieved original artifact bytes Format: original_artifact Inspected artifact
Source location Reviewed profile summary (2026-09-16): evidence-official-578439da3f3a3a476b7f, evidence-official-56e5abfb5f12f1cd3b20, evidence-official-bc0327ef2ea6107e1773: Paper: Unifying DNA sequence-to-function model and Discussion; README.md: Model weights and licensing; Supplementary Methods: Model (p.9), ENCODE RNA-seq Data (p.3), Contact maps Context-only references	AlphaGenome official resource Original source ↗ Reviewed profile summary (2026-09-16): evidence-official-578439da3f3a3a476b7f, evidence-official-56e5abfb5f12f1cd3b20, evidence-official-bc0327ef2ea6107e1773: Paper: Unifying DNA sequence-to-function model and Discussion; README.md: Model weights and licensing; Supplementary Methods: Model (p.9), ENCODE RNA-seq Data (p.3), Contact maps Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: Not recorded Retrieved: 2026-09-16T10:50:02Z	not individually reviewed No individual claim review recorded Audit details Field: `attributes.source_locator` Source artifact SHA-256: `Not recorded` Hash scope: Hash scope not separately documented; inspect source record
Source location Reviewed profile summary (2026-09-16): evidence-official-578439da3f3a3a476b7f, evidence-official-56e5abfb5f12f1cd3b20, evidence-official-bc0327ef2ea6107e1773: Paper: Unifying DNA sequence-to-function model and Discussion; README.md: Model weights and licensing; Supplementary Methods: Model (p.9), ENCODE RNA-seq Data (p.3), Contact maps Context-only references	alphagenome: Journal full-text XML Original source ↗ Reviewed profile summary (2026-09-16): evidence-official-578439da3f3a3a476b7f, evidence-official-56e5abfb5f12f1cd3b20, evidence-official-bc0327ef2ea6107e1773: Paper: Unifying DNA sequence-to-function model and Discussion; README.md: Model weights and licensing; Supplementary Methods: Model (p.9), ENCODE RNA-seq Data (p.3), Contact maps Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: Retrieved page snapshot; no immutable publisher revision supplied Retrieved: 2026-09-16T19:53:03.009088+00:00	not individually reviewed No individual claim review recorded Audit details Field: `attributes.source_locator` Source artifact SHA-256: `d159b791fc6cb7b679c151727b7b05a6e5b6388b08a89b675014983d85b6df36` Hash scope: SHA-256 of retrieved original artifact bytes Format: original_artifact Inspected artifact

How to read the evidence

Sources and history

Release 2026-10-23-5347695500ed · Record review: source checked

4 source records and release history

AlphaGenome official resource · Original source · Not reported
google-deepmind/alphagenome_research: README.md · Original source · 0db53bd4352c66d1e00a049a81da373a066e6670
alphagenome: Journal full-text XML · Original source · Retrieved page snapshot; no immutable publisher revision supplied
alphagenome-supp: Publisher supplementary archive · Original source · Retrieved page snapshot; no immutable publisher revision supplied

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Technical metadata and extraction receipts

Stable ID: metadata-correction-2f686f7a19b9ef14ea2c

areas: dna-genomes
method types: foundation_model
field: description
previous value: Existing candidate catalogue entry; exact checkpoint and metadata require primary-source review.
value: AlphaGenome predicts regulatory activity and variant effects from long DNA sequences, with outputs for expression, splicing, chromatin and contact maps.
source locator: Reviewed profile summary (2026-09-16): evidence-official-578439da3f3a3a476b7f, evidence-official-56e5abfb5f12f1cd3b20, evidence-official-bc0327ef2ea6107e1773: Paper: Unifying DNA sequence-to-function model and Discussion; README.md: Model weights and licensing; Supplementary Methods: Model (p.9), ENCODE RNA-seq Data (p.3), Contact maps
review: method: automated-source-review; ai-assisted-source-review; reviewer: claude; reviewer note: Extractor: Claude integrator agent for issue #88. Reviewer: a separate Claude review agent, independent of the extractor; no human review claimed.; date: 2026-10-11; method note: Compared the store diff with origin/main, read each new description against its cited source passage and checked the licence of each new source record.; note: Approved. Checked the new sources' licences against the arXiv abstract pages and Europe PMC, the 7 scFoundation pipeline descriptions against their abstracts, the language-model descriptions against their model cards and reports, and the TAPE architecture figures against the TAPE paper; all correct. The catalogue entries reuse reviewed profile summaries.; receipt: data/omics/qa-descriptions-20261011-b/review.json

Related records

subject: AlphaGenome

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