reference_standard_definition: dna-pathogen-20261011-hu2026-protocol-crs
Reference standard definition of Organism-level agreement with composite reference standard (CRS), 62 BALF specimens (Hu et al. 2026)
The composite reference standard adds to the clinical microbiological tests the organisms that lacked targeted testing results but were detected by both sequencing workflows (MGI and HD-ONT) under the reporting criteria; 31 organisms were added this way.
Descriptive fact transcribed from the pinned source.
Evidence
Source checking verifies the cited claim or transcription. It does not establish independent reproduction.
Evidence table
Inspect claims, sources and review details
Trace each statement to its source and review. A context-only reference supports the record generally; it does not verify an individual field. Source checking does not reproduce an experiment.
One row per statement and cited source. Multiple citations are not independent evaluations. Shared locators are labelled explicitly.
6 evidence rows matching the loaded filters
| Property and statement | Original source and location | Review and provenance |
|---|---|---|
| Claimed field reference_standard_definition Context-only references | Benchmarking next- versus third-generation sequencing in metagenomics: performance metrics and diagnostic efficacy Methods 'Clinical performance evaluation and reference standards' paragraph 1, third comparator; Results 'Diagnostic performance for clinical samples' paragraph 3 Version: Microbiology Spectrum 14(7):e03993-25, published 2026-06-03; PMC13339908 full-text XML | not individually reviewed No individual claim review recorded Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| Source location Methods 'Clinical performance evaluation and reference standards' paragraph 1, third comparator; Results 'Diagnostic performance for clinical samples' paragraph 3 Context-only references | Benchmarking next- versus third-generation sequencing in metagenomics: performance metrics and diagnostic efficacy Methods 'Clinical performance evaluation and reference standards' paragraph 1, third comparator; Results 'Diagnostic performance for clinical samples' paragraph 3 Version: Microbiology Spectrum 14(7):e03993-25, published 2026-06-03; PMC13339908 full-text XML | not individually reviewed No individual claim review recorded Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| Claimed value The composite reference standard adds to the clinical microbiological tests the organisms that lacked targeted testing results but were detected by both sequencing workflows (MGI and HD-ONT) under the reporting criteria; 31 organisms were added this way. Context-only references | Benchmarking next- versus third-generation sequencing in metagenomics: performance metrics and diagnostic efficacy Methods 'Clinical performance evaluation and reference standards' paragraph 1, third comparator; Results 'Diagnostic performance for clinical samples' paragraph 3 Version: Microbiology Spectrum 14(7):e03993-25, published 2026-06-03; PMC13339908 full-text XML | not individually reviewed No individual claim review recorded Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| Description Descriptive fact transcribed from the pinned source. Context-only references | Benchmarking next- versus third-generation sequencing in metagenomics: performance metrics and diagnostic efficacy Methods 'Clinical performance evaluation and reference standards' paragraph 1, third comparator; Results 'Diagnostic performance for clinical samples' paragraph 3 Version: Microbiology Spectrum 14(7):e03993-25, published 2026-06-03; PMC13339908 full-text XML | not individually reviewed No individual claim review recorded Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| Relationship: subject dna-pathogen-20261011-hu2026-protocol-crs Context-only references | Benchmarking next- versus third-generation sequencing in metagenomics: performance metrics and diagnostic efficacy Methods 'Clinical performance evaluation and reference standards' paragraph 1, third comparator; Results 'Diagnostic performance for clinical samples' paragraph 3 Version: Microbiology Spectrum 14(7):e03993-25, published 2026-06-03; PMC13339908 full-text XML | not individually reviewed No individual claim review recorded Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| Name reference_standard_definition: dna-pathogen-20261011-hu2026-protocol-crs Context-only references | Benchmarking next- versus third-generation sequencing in metagenomics: performance metrics and diagnostic efficacy Methods 'Clinical performance evaluation and reference standards' paragraph 1, third comparator; Results 'Diagnostic performance for clinical samples' paragraph 3 Version: Microbiology Spectrum 14(7):e03993-25, published 2026-06-03; PMC13339908 full-text XML | not individually reviewed No individual claim review recorded Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
Sources and history
Release 2026-10-22-1b7cf027e4f6 · Record review: source checked
1 source record and release history
- Benchmarking next- versus third-generation sequencing in metagenomics: performance metrics and diagnostic efficacy · Original source · Microbiology Spectrum 14(7):e03993-25, published 2026-06-03; PMC13339908 full-text XML
Technical metadata and extraction receipts
Stable ID: dna-pathogen-20261011-hu2026-claim-crs-incorporation
- field
- reference_standard_definition
- value
- The composite reference standard adds to the clinical microbiological tests the organisms that lacked targeted testing results but were detected by both sequencing workflows (MGI and HD-ONT) under the reporting criteria; 31 organisms were added this way.
- source locator
- Methods 'Clinical performance evaluation and reference standards' paragraph 1, third comparator; Results 'Diagnostic performance for clinical samples' paragraph 3
- review
- method: source-hash-verification; independent-cell-check; scope-review; reviewer: claude; reviewer note: Separate Claude review agent (reviewer-path), independent of the extractor; no human review claimed; date: 2026-10-11; artifact sha256: 555995fd870d878dd0e6c112064bbf1d2535a1cb1af17f70570ecc11774caa2d; retrieval url: https://www.ebi.ac.uk/europepmc/webservices/rest/PMC13339908/fullTextXML; method note: Transcribed from the pinned article XML text.; note: Re-downloaded the pinned artifact and matched its SHA-256; compared every value with a separate stdlib parser written for this review (the extractor's script was not run) and checked a stratified sample by hand against the rendered table.