Gene-specific manual BRCA review baseline
Source-supported expert curation workflow; complete classification is distinct from BayesDel functional calibration.
Evaluation results
0 evaluations · 0 results. Different protocols are not a single leaderboard.
Applied filters: All linked evaluations
No evaluations linked in this release.
Source checking is not independent reproduction. Release 2026-09-30-e37e3ab1284d.
Applicable tests and references
Applicability is distinct from a completed evaluation.
- ENIGMA specification pilot resolution · Proposed association
- BRCA1 BayesDel evidence calibration · Proposed association
- BRCA2 BayesDel evidence calibration · Proposed association
Evidence
Source checking verifies the cited claim or transcription. It does not establish independent reproduction.
Evidence table
Inspect claims, sources and review details
Trace each statement to its source and review. A context-only reference supports the record generally; it does not verify an individual field. Source checking does not reproduce an experiment.
One row per statement and cited source. Multiple citations are not independent evaluations. Shared locators are labelled explicitly.
8 evidence rows matching the loaded filters
| Property and statement | Original source and location | Review and provenance |
|---|---|---|
| attributes.applicability source_supported Context-only references | Evidence-based recommendations for gene-specific ACMG/AMP variant classification from the ClinGen ENIGMA BRCA1 and BRCA2 Variant Curation Expert Panel No field-specific location recorded Version: 2024 final article; reported VCEP specifications v1.0 | not individually reviewed No individual claim review recorded Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| attributes.baseline_type conventional_workflow Context-only references | Evidence-based recommendations for gene-specific ACMG/AMP variant classification from the ClinGen ENIGMA BRCA1 and BRCA2 Variant Curation Expert Panel No field-specific location recorded Version: 2024 final article; reported VCEP specifications v1.0 | not individually reviewed No individual claim review recorded Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| description Source-supported expert curation workflow; complete classification is distinct from BayesDel functional calibration. Context-only references | Evidence-based recommendations for gene-specific ACMG/AMP variant classification from the ClinGen ENIGMA BRCA1 and BRCA2 Variant Curation Expert Panel No field-specific location recorded Version: 2024 final article; reported VCEP specifications v1.0 | not individually reviewed No individual claim review recorded Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| Relationship: applicable to uc-clinical-20260930-enigma-brca1-protocol Context-only references | Evidence-based recommendations for gene-specific ACMG/AMP variant classification from the ClinGen ENIGMA BRCA1 and BRCA2 Variant Curation Expert Panel No field-specific location recorded Version: 2024 final article; reported VCEP specifications v1.0 | not individually reviewed No individual claim review recorded Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| Relationship: applicable to uc-clinical-20260930-enigma-brca2-protocol Context-only references | Evidence-based recommendations for gene-specific ACMG/AMP variant classification from the ClinGen ENIGMA BRCA1 and BRCA2 Variant Curation Expert Panel No field-specific location recorded Version: 2024 final article; reported VCEP specifications v1.0 | not individually reviewed No individual claim review recorded Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| Relationship: applicable to uc-clinical-20260930-enigma-pilot-protocol Context-only references | Evidence-based recommendations for gene-specific ACMG/AMP variant classification from the ClinGen ENIGMA BRCA1 and BRCA2 Variant Curation Expert Panel No field-specific location recorded Version: 2024 final article; reported VCEP specifications v1.0 | not individually reviewed No individual claim review recorded Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| Relationship: configuration uc-clinical-20260930-enigma-v10-manual Context-only references | Evidence-based recommendations for gene-specific ACMG/AMP variant classification from the ClinGen ENIGMA BRCA1 and BRCA2 Variant Curation Expert Panel No field-specific location recorded Version: 2024 final article; reported VCEP specifications v1.0 | not individually reviewed No individual claim review recorded Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| name Gene-specific manual BRCA review baseline Context-only references | Evidence-based recommendations for gene-specific ACMG/AMP variant classification from the ClinGen ENIGMA BRCA1 and BRCA2 Variant Curation Expert Panel No field-specific location recorded Version: 2024 final article; reported VCEP specifications v1.0 | not individually reviewed No individual claim review recorded Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
Sources and history
View linked audit checks and correction history
Release 2026-09-30-e37e3ab1284d · Record review: source checked
1 source records and release history
- Evidence-based recommendations for gene-specific ACMG/AMP variant classification from the ClinGen ENIGMA BRCA1 and BRCA2 Variant Curation Expert Panel · Original source · 2024 final article; reported VCEP specifications v1.0
Technical metadata and extraction receipts
Stable ID: uc-clinical-20260930-baseline-enigma-manual
- areas
- dna-genomes
- contexts
- clinical_research
- baseline type
- conventional_workflow
- applicability
- source_supported
- review
- method: automated_source_review; reviewer: Codex clinical coverage worker; date: 2026-09-30; note: Transcription from inspected primary source. No execution, independent replication or human scientific review.; source id: uc-clinical-20260930-source-enigma
Related records
- configuration: ClinGen ENIGMA v1.0 manual criteria-based curation
- applicable to: ENIGMA specification pilot resolution
- applicable to: BRCA1 BayesDel evidence calibration
- applicable to: BRCA2 BayesDel evidence calibration