rewirebio.iobenchmarks
Evidence and investigation

Contested results

Where one study disagrees with what other studies report for the same models, and what we are doing to resolve each case.

These are automatic leads, not findings of error. Each release, a check compares how every study ranks the models it shares with other studies. It flags a study that reverses the order the others agree on, or whose gap to a shared reference model lies well outside theirs. Different tasks, populations or metrics often explain a flag.

A flag never hides a result. Flagged results stay in every table, page and download, marked Contested. A result is withheld only when a reviewer marks it disputed.

How the check works, and how each follow-up is recorded: discrepancies between studies.

In this release

  • 220open
  • 0settled
  • 1resolved
  • 1high severity
  • 12medium severity
  • 208low severity

Release 2026-10-23-5347695500ed · 221 findings in all · rules version 3

Findings

Status: All · Open · Settled · Resolved

Severity: All · High · Medium · Low

State: All · Not yet reviewed · Confirmed error

Showing findings that compare DNABERT-2. All models

3 findings match, most severe first.

DNABERT-2 and RNA-FM: mRNABench: A curated benchmark for mature mRNA property and function prediction reverses the order

  • Medium severity
  • Not yet reviewed
  • Ordering reversal
  • Different tasks across studies

mRNABench: A curated benchmark for mature mRNA property and function prediction ranks DNABERT-2 above RNA-FM in 7 of 7 comparisons; other studies rank RNA-FM above DNABERT-2 in 30 of 30.

2 papers rank RNA-FM above DNABERT-2 in all 30 comparisons that are not ties (4 are ties). MRNABench ranks DNABERT-2 above RNA-FM in all 7 comparisons that are not ties (3 are ties).

Comparisons in which each paper scores RNA-FM or DNABERT-2 higher2 other papers: RNA-FM higher in 30, DNABERT-2 higher in 0, 4 ties. mRNABench (disagrees): RNA-FM higher in 0, DNABERT-2 higher in 7, 3 ties.2 other papers30 RNA-FM higher304 tie4Disagrees: mRNABenchmRNABench: A curated benchmark for mature mRNA property and function prediction3 tie37 DNABERT-2 higher7
RNA-FM higherTieDNABERT-2 higher
Compared
DNABERT-2, RNA-FM

Not reviewed yet.

DNABERT-2 and HyenaDNA: Comparative Analysis of Deep Learning Models for Predicting Causative Regulatory Variants reverses the order

  • Low severity
  • Not yet reviewed
  • Ordering reversal
  • Different tasks across studies

Comparative Analysis of Deep Learning Models for Predicting Causative Regulatory Variants ranks HyenaDNA above DNABERT-2 in 3 of 4 comparisons; other studies rank DNABERT-2 above HyenaDNA in 89 of 108.

3 papers rank DNABERT-2 above HyenaDNA in 89 of their 115 comparisons and HyenaDNA higher in 19; 7 are ties. Comparative Analysis of Deep Learning… ranks HyenaDNA above DNABERT-2 in 3 of its 4 comparisons and DNABERT-2 higher in 1.

Comparisons in which each paper scores DNABERT-2 or HyenaDNA higher3 other papers: DNABERT-2 higher in 89, HyenaDNA higher in 19, 7 ties. Comparative Analysis of Deep Learning… (disagrees): DNABERT-2 higher in 1, HyenaDNA higher in 3, 0 ties.3 other papers89 DNABERT-2 higher897 tie19 HyenaDNA higher19Disagrees: Comparative Analysis of Deep Learning…Comparative Analysis of Deep Learning Models for Predicting Causative Regulatory Variants1 DNABERT-2 higher13 HyenaDNA higher3
DNABERT-2 higherTieHyenaDNA higher
Compared
DNABERT-2, HyenaDNA

Not reviewed yet.

DNABERT-2 and Evo: GENEB leaderboard (leaderboard.json, 13 task-type aggregates) reverses the order

  • Low severity
  • Not yet reviewed
  • Ordering reversal
  • Different tasks across studies

GENEB leaderboard (leaderboard.json, 13 task-type aggregates) ranks DNABERT-2 above Evo in 35 of 45 comparisons; other studies rank Evo above DNABERT-2 in 6 of 6.

Zero-shot benchmarking of RNA language… ranks Evo above DNABERT-2 in all 6 of its comparisons. GENEB leaderboard ranks DNABERT-2 above Evo in 35 of its 45 comparisons and Evo higher in 10.

Comparisons in which each paper scores Evo or DNABERT-2 higherZero-shot benchmarking of RNA language…: Evo higher in 6, DNABERT-2 higher in 0, 0 ties. GENEB leaderboard (disagrees): Evo higher in 10, DNABERT-2 higher in 35, 0 ties.Zero-shot benchmarking of RNA language…6 Evo higher6Disagrees: GENEB leaderboardGENEB leaderboard (leaderboard.json, 13 task-type aggregates)10 Evo higher1035 DNABERT-2 higher35
Evo higherTieDNABERT-2 higher
Compared
DNABERT-2, Evo

Not reviewed yet.