rewirebio.iobenchmarks
Evidence and investigation

Contested results

Where one study disagrees with what other studies report for the same models, and what we are doing to resolve each case.

These are automatic leads, not findings of error. Each release, a check compares how every study ranks the models it shares with other studies. It flags a study that reverses the order the others agree on, or whose gap to a shared reference model lies well outside theirs. Different tasks, populations or metrics often explain a flag.

A flag never hides a result. Flagged results stay in every table, page and download, marked Contested. A result is withheld only when a reviewer marks it disputed.

How the check works, and how each follow-up is recorded: discrepancies between studies.

In this release

  • 121open
  • 5settled
  • 7resolved
  • 1medium severity
  • 132low severity

Release 2026-11-02-a7f03c9e55a5 · 133 findings in all · rules version 4

Findings

Status: All · Open · Settled · Resolved

Severity: All · Medium · Low

State: All · Not yet reviewed · Under investigation · Explained · Confirmed error · Not a real disagreement

Showing findings that compare ProGen2. All models

1 finding matches, most severe first.

ProGen2 and Tranception: ProteinGym: Large-Scale Benchmarks for Protein Fitness Prediction and Design and Livesey and Marsh 2025, Genome Biology 26:104 (Europe PMC full text XML) disagree

  • Low severity
  • Not yet reviewed
  • two-study-conflict
  • different-task

ProteinGym: Large-Scale Benchmarks for Protein Fitness Prediction and Design ranks Tranception above ProGen2 in 19 of 19 comparisons; Livesey and Marsh 2025, Genome Biology 26:104 (Europe PMC full text XML) ranks ProGen2 above Tranception in 6 of 6 comparisons. No other study gives a verdict, so neither is the outlier.

2 papers rank ProGen2 above Tranception in 6 of their 26 comparisons and Tranception higher in 19; 1 is a tie. Of those papers, ProteinGym ranks Tranception higher on its own (19 of 20).

Comparisons in which each paper scores ProGen2 or Tranception higher2 other papers: ProGen2 higher in 6, Tranception higher in 19, 1 tie.2 other papers6 ProGen2 higher61 tie19 Tranception higher19
ProGen2 higherTieTranception higher
Compared
ProGen2, Tranception

Not reviewed yet.