rewirebio.iobenchmarks
Evidence and investigation

Contested results

Where one study disagrees with what other studies report for the same models, and what we are doing to resolve each case.

These are automatic leads, not findings of error. Each release, a check compares how every study ranks the models it shares with other studies. It flags a study that reverses the order the others agree on, or whose gap to a shared reference model lies well outside theirs. Different tasks, populations or metrics often explain a flag.

A flag never hides a result. Flagged results stay in every table, page and download, marked Contested. A result is withheld only when a reviewer marks it disputed.

How the check works, and how each follow-up is recorded: discrepancies between studies.

In this release

  • 121open
  • 5settled
  • 7resolved
  • 1medium severity
  • 132low severity

Release 2026-11-02-a7f03c9e55a5 · 133 findings in all · rules version 4

Findings

Status: All · Open · Settled · Resolved

Severity: All · Medium · Low

State: All · Not yet reviewed · Under investigation · Explained · Confirmed error · Not a real disagreement

Showing findings that compare SuSPect. All models

2 findings match, most severe first.

SuSPect and MetaLR: Clinical likelihood ratios and balanced accuracy for 44 in silico tools against multiple large-scale functional assays of cancer susceptibility genes and Livesey and Marsh 2025, Genome Biology 26:104 (Europe PMC full text XML) disagree

  • Low severity
  • Not yet reviewed
  • two-study-conflict
  • unknown

Clinical likelihood ratios and balanced accuracy for 44 in silico tools against multiple large-scale functional assays of cancer susceptibility genes ranks MetaLR above SuSPect in 4 of 5 comparisons; Livesey and Marsh 2025, Genome Biology 26:104 (Europe PMC full text XML) ranks SuSPect above MetaLR in 6 of 7 comparisons. No other study gives a verdict, so neither is the outlier.

2 papers rank SuSPect above MetaLR in 7 of their 13 comparisons and MetaLR higher in 5; 1 is a tie. Of those papers, Clinical likelihood ratios and balanced… ranks MetaLR higher on its own (4 of 6).

Comparisons in which each paper scores SuSPect or MetaLR higher2 other papers: SuSPect higher in 7, MetaLR higher in 5, 1 tie.2 other papers7 SuSPect higher71 tie5 MetaLR higher5
SuSPect higherTieMetaLR higher
Compared
SuSPect, MetaLR

Not reviewed yet.

SuSPect and MetaSVM: Clinical likelihood ratios and balanced accuracy for 44 in silico tools against multiple large-scale functional assays of cancer susceptibility genes and Livesey and Marsh 2025, Genome Biology 26:104 (Europe PMC full text XML) disagree

  • Low severity
  • Not yet reviewed
  • two-study-conflict
  • unknown

Clinical likelihood ratios and balanced accuracy for 44 in silico tools against multiple large-scale functional assays of cancer susceptibility genes ranks MetaSVM above SuSPect in 5 of 6 comparisons; Livesey and Marsh 2025, Genome Biology 26:104 (Europe PMC full text XML) ranks SuSPect above MetaSVM in 7 of 7 comparisons. No other study gives a verdict, so neither is the outlier.

2 papers rank SuSPect above MetaSVM in 8 of their 13 comparisons and MetaSVM higher in 5. Of those papers, Clinical likelihood ratios and balanced… ranks MetaSVM higher on its own (5 of 6).

Comparisons in which each paper scores SuSPect or MetaSVM higher2 other papers: SuSPect higher in 8, MetaSVM higher in 5, 0 ties.2 other papers8 SuSPect higher85 MetaSVM higher5
SuSPect higherTieMetaSVM higher
Compared
SuSPect, MetaSVM

Not reviewed yet.