rewirebio.iobenchmarks
Evidence and investigation

Contested results

Where one study disagrees with what other studies report for the same models, and what we are doing to resolve each case.

These are automatic leads, not findings of error. Each release, a check compares how every study ranks the models it shares with other studies. It flags a study that reverses the order the others agree on, or whose gap to a shared reference model lies well outside theirs. Different tasks, populations or metrics often explain a flag.

A flag never hides a result. Flagged results stay in every table, page and download, marked Contested. A result is withheld only when a reviewer marks it disputed.

How the check works, and how each follow-up is recorded: discrepancies between studies.

In this release

  • 121open
  • 5settled
  • 7resolved
  • 1medium severity
  • 132low severity

Release 2026-11-02-a7f03c9e55a5 · 133 findings in all · rules version 4

Findings

Status: All · Open · Settled · Resolved

Severity: All · Medium · Low

State: All · Not yet reviewed · Under investigation · Explained · Confirmed error · Not a real disagreement

Showing findings that compare Borzoi. All models

2 findings match, most severe first.

Borzoi and HyenaDNA: Comparative Analysis of Deep Learning Models for Predicting Causative Regulatory Variants and TraitGym official metrics: AUPRC by chromosome, weighted average (Hugging Face dataset songlab/TraitGym) disagree

  • Low severity
  • Not yet reviewed
  • two-study-conflict
  • unknown

Comparative Analysis of Deep Learning Models for Predicting Causative Regulatory Variants ranks HyenaDNA above Borzoi in 3 of 4 comparisons; TraitGym official metrics: AUPRC by chromosome, weighted average (Hugging Face dataset songlab/TraitGym) ranks Borzoi above HyenaDNA in 2 of 2 comparisons. No other study gives a verdict, so neither is the outlier.

2 papers rank Borzoi above HyenaDNA in 3 of their 6 comparisons and HyenaDNA higher in 3. Of those papers, Comparative Analysis of Deep Learning… ranks HyenaDNA higher on its own (3 of 4).

Comparisons in which each paper scores Borzoi or HyenaDNA higher2 other papers: Borzoi higher in 3, HyenaDNA higher in 3, 0 ties.2 other papers3 Borzoi higher33 HyenaDNA higher3
Borzoi higherTieHyenaDNA higher
Compared
Borzoi, HyenaDNA

Not reviewed yet.

Borzoi and Sei: GUANinE v1.1 reveals complementarity of supervised and genomic language models and Comparative Analysis of Deep Learning Models for Predicting Causative Regulatory Variants disagree

  • Low severity
  • Not yet reviewed
  • two-study-conflict
  • unknown

GUANinE v1.1 reveals complementarity of supervised and genomic language models ranks Borzoi above Sei in 6 of 6 comparisons; Comparative Analysis of Deep Learning Models for Predicting Causative Regulatory Variants ranks Sei above Borzoi in 4 of 4 comparisons. No other study gives a verdict, so neither is the outlier.

2 papers rank Borzoi above Sei in 6 of their 11 comparisons and Sei higher in 4; 1 is a tie. Of those papers, Comparative Analysis of Deep Learning… ranks Sei higher on its own (4 of 4).

Comparisons in which each paper scores Borzoi or Sei higher2 other papers: Borzoi higher in 6, Sei higher in 4, 1 tie.2 other papers6 Borzoi higher61 tie14 Sei higher4
Borzoi higherTieSei higher
Compared
Borzoi, Sei

Not reviewed yet.