rewirebio.iobenchmarks
Evidence and investigation

Contested results

Where one study disagrees with what other studies report for the same models, and what we are doing to resolve each case.

These are automatic leads, not findings of error. Each release, a check compares how every study ranks the models it shares with other studies. It flags a study that reverses the order the others agree on, or whose gap to a shared reference model lies well outside theirs. Different tasks, populations or metrics often explain a flag.

A flag never hides a result. Flagged results stay in every table, page and download, marked Contested. A result is withheld only when a reviewer marks it disputed.

How the check works, and how each follow-up is recorded: discrepancies between studies.

In this release

  • 121open
  • 5settled
  • 7resolved
  • 1medium severity
  • 132low severity

Release 2026-11-02-a7f03c9e55a5 · 133 findings in all · rules version 4

Findings

Status: All · Open · Settled · Resolved

Severity: All · Medium · Low

State: All · Not yet reviewed · Under investigation · Explained · Confirmed error · Not a real disagreement

Showing findings that compare ChromBPNet. All models

2 findings match, most severe first.

ChromBPNet and Caduceus: GUANinE v1.1 reveals complementarity of supervised and genomic language models and Comparative Analysis of Deep Learning Models for Predicting Causative Regulatory Variants disagree

  • Low severity
  • Not yet reviewed
  • two-study-conflict
  • unknown

GUANinE v1.1 reveals complementarity of supervised and genomic language models ranks Caduceus above ChromBPNet in 6 of 6 comparisons; Comparative Analysis of Deep Learning Models for Predicting Causative Regulatory Variants ranks ChromBPNet above Caduceus in 4 of 4 comparisons. No other study gives a verdict, so neither is the outlier.

2 papers rank ChromBPNet above Caduceus in 4 of their 10 comparisons and Caduceus higher in 6. Of those papers, GUANinE v1.1 reveals complementarity… ranks Caduceus higher on its own (6 of 6).

Comparisons in which each paper scores ChromBPNet or Caduceus higher2 other papers: ChromBPNet higher in 4, Caduceus higher in 6, 0 ties.2 other papers4 ChromBPNet higher46 Caduceus higher6
ChromBPNet higherTieCaduceus higher
Compared
ChromBPNet, Caduceus

Not reviewed yet.

ChromBPNet and GENA-LM: GUANinE v1.1 reveals complementarity of supervised and genomic language models and Comparative Analysis of Deep Learning Models for Predicting Causative Regulatory Variants disagree

  • Low severity
  • Not yet reviewed
  • two-study-conflict
  • unknown

GUANinE v1.1 reveals complementarity of supervised and genomic language models ranks GENA-LM above ChromBPNet in 3 of 4 comparisons; Comparative Analysis of Deep Learning Models for Predicting Causative Regulatory Variants ranks ChromBPNet above GENA-LM in 4 of 4 comparisons. No other study gives a verdict, so neither is the outlier.

2 papers rank ChromBPNet above GENA-LM in 5 of their 10 comparisons and GENA-LM higher in 3; 2 are ties. Of those papers, GUANinE v1.1 reveals complementarity… ranks GENA-LM higher on its own (3 of 6).

Comparisons in which each paper scores ChromBPNet or GENA-LM higher2 other papers: ChromBPNet higher in 5, GENA-LM higher in 3, 2 ties.2 other papers5 ChromBPNet higher52 tie23 GENA-LM higher3
ChromBPNet higherTieGENA-LM higher
Compared
ChromBPNet, GENA-LM

Not reviewed yet.