Result

0.79 recall

nguyen2023-spotmas-too-dnn-validation recall (tissue of origin, five cancer types; lung cancer patients (printed as accuracy); stage III)

Tested configuration: SPOT-MAS tissue-of-origin Deep neural network (DNN)
Protocol: SPOT-MAS five-class tissue of origin, independent validation cohort
Dataset: SPOT-MAS validation cohort, 239 non-metastatic cancer patients (five cancer types)
Procedure: ctdnameth-20261009-protocol-nguyen2023-spotmas-too-validation
Evaluation: SPOT-MAS tissue of origin, DNN (validation)
Coverage: 24 cancer patients scored (n printed in cell N18)
Uncertainty: Not reported by the source
Evidence: Author-reported evaluation · source checkedMultimodal analysis of methylomics and fragmentomics in plasma cell-free DNA for multi-cancer early detection and localization; Nguyen et al. 2023, Supplementary file 1 (Tables S1-S11) · Supplementary file 1, sheet 'Table S9', P18; Validation block; row 'Lung'; column 'DNN' under 'Stage III' (n in N18)

A source-checked result verifies the numerical transcription, not every model or protocol detail. Evaluation metadata: source checked. Source checked does not mean independently reproduced.

Reproduction

Split: Independent validation cohort
Adaptation: Not reported
Scoring implementation: Correctly assigned patients / patients in the stratum

No execution recipe has been verified for this exact configuration and evaluation. A benchmark's general instructions may use different inputs, splits or model settings.

Reproducing this published result requires matching its model configuration, data, split and scorer. Source checking or a successful smoke test does not establish score reproduction.

Evidence

Source checking verifies the cited claim or transcription. It does not establish independent reproduction.

Evidence table

Inspect claims, sources and review details

Trace each statement to its source and review. A context-only reference supports the record generally; it does not verify an individual field. Source checking does not reproduce an experiment.

One row per statement and cited source. Multiple citations are not independent evaluations. Shared locators are labelled explicitly.

2 evidence rows matching the loaded filters

Claims, original sources and review scope · Release 2026-10-09-8cc1db47c7f9
Property and statement	Original source and location	Review and provenance
Reported result 0.79 Individual claims	Multimodal analysis of methylomics and fragmentomics in plasma cell-free DNA for multi-cancer early detection and localization Original source ↗ Supplementary file 1, sheet 'Table S9', P18; Validation block; row 'Lung'; column 'DNN' under 'Stage III' (n in N18) Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: eLife 12:RP89083, version of record published 2023-10-11; PMC10567114 full-text XML Retrieved: 2026-10-09T20:04:09Z	source checked ["source-hash-verification","deterministic-table-parse","independent-cell-check"] · 2026-10-09 author reported Audit details Extracted by deterministic parse of the pinned XLSX cell XML (extract/rawxlsx.py, extract/extract_ctdna_methylation.py) with row and column labels asserted. printed_value is the shortest round-trip decimal of the stored cell value, or the displayed text where the workbook applies a fixed-decimals number format (recorded in workbook_number_format); raw_xml_value keeps the stored text. Independent review 2026-10-09: value and identity match the source. Field: `attributes.printed_value` Source artifact SHA-256: `e09cfb58a6055e89ffa7b553a37539e1687f0fcb26970b7b25eb9eda8e09cfa8` Hash scope: Hash scope not separately documented; inspect source record Inspected artifact Extraction artifact SHA-256: `4797d7ea0fde127bfa54cf0bdf717d859092c0442ab996a0af10cc5ce17b7331` Extraction artifact
Reported result 0.79 Individual claims	Nguyen et al. 2023, Supplementary file 1 (Tables S1-S11) Original source ↗ Supplementary file 1, sheet 'Table S9', P18; Validation block; row 'Lung'; column 'DNN' under 'Stage III' (n in N18) Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: Supplementary file 1 (elife-89083-supp1.xlsx) of eLife 12:RP89083, PMC open-access copy PMC10567114.1 Retrieved: 2026-10-09T20:03:58Z	source checked ["source-hash-verification","deterministic-table-parse","independent-cell-check"] · 2026-10-09 author reported Audit details Extracted by deterministic parse of the pinned XLSX cell XML (extract/rawxlsx.py, extract/extract_ctdna_methylation.py) with row and column labels asserted. printed_value is the shortest round-trip decimal of the stored cell value, or the displayed text where the workbook applies a fixed-decimals number format (recorded in workbook_number_format); raw_xml_value keeps the stored text. Independent review 2026-10-09: value and identity match the source. Field: `attributes.printed_value` Source artifact SHA-256: `4797d7ea0fde127bfa54cf0bdf717d859092c0442ab996a0af10cc5ce17b7331` Hash scope: Hash scope not separately documented; inspect source record Inspected artifact Extraction artifact SHA-256: `4797d7ea0fde127bfa54cf0bdf717d859092c0442ab996a0af10cc5ce17b7331` Extraction artifact

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Sources and history

Release 2026-10-09-8cc1db47c7f9 · Record review: source checked

2 source records and release history

Multimodal analysis of methylomics and fragmentomics in plasma cell-free DNA for multi-cancer early detection and localization · Original source · eLife 12:RP89083, version of record published 2023-10-11; PMC10567114 full-text XML
Nguyen et al. 2023, Supplementary file 1 (Tables S1-S11) · Original source · Supplementary file 1 (elife-89083-supp1.xlsx) of eLife 12:RP89083, PMC open-access copy PMC10567114.1

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Technical metadata and extraction receipts

Stable ID: ctdnameth-20261009-result-nguyen2023-spotmas-too-dnn-validation-lung-stage-iii

metric: recall
metric qualifier: tissue of origin, five cancer types; lung cancer patients (printed as accuracy); stage III
metric direction: higher
unit: fraction
printed value: 0.79
numeric value: 0.79
source locator: Supplementary file 1, sheet 'Table S9', P18; Validation block; row 'Lung'; column 'DNN' under 'Stage III' (n in N18)
raw xml value: 0.79
review: method: source-hash-verification; deterministic-table-parse; independent-cell-check; method note: Re-downloaded the workbook and matched its SHA-256. Read the cell with a separate stdlib OOXML reader written for this review (shared strings, raw cell text and number format from styles.xml); the extractor's scripts were not imported or run. Checked raw text, printed value (fixed-decimals display where the cell format applies one, otherwise shortest round-trip decimal), numeric value, metric, qualifier, unit, direction, denominator or scored n, and the linked evaluation's configuration and protocol against the row and column headers.; reviewer: claude; reviewer note: Separate Claude review agent, independent of the extractor; no human review claimed; date: 2026-10-09; artifact sha256: 4797d7ea0fde127bfa54cf0bdf717d859092c0442ab996a0af10cc5ce17b7331; retrieval url: https://pmc-oa-opendata.s3.amazonaws.com/PMC10567114.1/elife-89083-supp1.xlsx; note: Extracted by deterministic parse of the pinned XLSX cell XML (extract/rawxlsx.py, extract/extract_ctdna_methylation.py) with row and column labels asserted. printed_value is the shortest round-trip decimal of the stored cell value, or the displayed text where the workbook applies a fixed-decimals number format (recorded in workbook_number_format); raw_xml_value keeps the stored text. Independent review 2026-10-09: value and identity match the source.
missing metadata: uncertainty: reason: unreported
coverage: scored: 24; unit: cancer patients; note: n printed in cell N18

Related records

evaluation: SPOT-MAS tissue of origin, DNN (validation)

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