metric_definition: ctdnameth-20261009-protocol-giuili2025-wgbs-tt-tumour-fraction-lod
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Evidence
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Inspect claims, sources and review details
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6 evidence rows matching the loaded filters
| Property and statement | Original source and location | Review and provenance |
|---|---|---|
| attributes.field metric_definition Context-only references | A benchmark of DNA methylation deconvolution methods for tumoral fraction estimation using DecoNFlow Preprint Results 'The tumoral fraction limit of detection' (page 11), Methods 'Evaluation metrics and missing values' (pages 26-27), Supplementary Table 2D Version: bioRxiv preprint version 1, posted 2025-11-27; not peer reviewed | not individually reviewed No individual claim review recorded Audit detailsField: Source artifact SHA-256: Hash scope: Not reproducible by re-download: bioRxiv rewrites the PDF on each download (ModDate and XMP dates set to the download time). A copy retrieved 2026-10-09T20:21:09Z has the same length (7,728,127 bytes) and SHA-256 fa7bcf8c25532f86dc99ed7d76a13a49ae70e29ab9f46559b3e0972e86aa9b96; resetting its three date stamps to any time on that day does not give the pinned hash, so another per-download field also differs. No result value is taken from this PDF. |
| attributes.source_locator Preprint Results 'The tumoral fraction limit of detection' (page 11), Methods 'Evaluation metrics and missing values' (pages 26-27), Supplementary Table 2D Context-only references | A benchmark of DNA methylation deconvolution methods for tumoral fraction estimation using DecoNFlow Preprint Results 'The tumoral fraction limit of detection' (page 11), Methods 'Evaluation metrics and missing values' (pages 26-27), Supplementary Table 2D Version: bioRxiv preprint version 1, posted 2025-11-27; not peer reviewed | not individually reviewed No individual claim review recorded Audit detailsField: Source artifact SHA-256: Hash scope: Not reproducible by re-download: bioRxiv rewrites the PDF on each download (ModDate and XMP dates set to the download time). A copy retrieved 2026-10-09T20:21:09Z has the same length (7,728,127 bytes) and SHA-256 fa7bcf8c25532f86dc99ed7d76a13a49ae70e29ab9f46559b3e0972e86aa9b96; resetting its three date stamps to any time on that day does not give the pinned hash, so another per-download field also differs. No result value is taken from this PDF. |
| attributes.value Lowest tumour fraction at which the estimated fractions of the ten replicates are significantly higher than those of 0% tumour samples (one-tailed unpaired Mann-Whitney U test, Benjamini-Hochberg adjusted p < 0.01), moving from higher to lower fractions. Tested grid (Supplementary Table 2D): 0.0001, 0.001, 0.003, 0.007, 0.01, 0.025, 0.05, 0.1, 0.25, 0.5. Context-only references | A benchmark of DNA methylation deconvolution methods for tumoral fraction estimation using DecoNFlow Preprint Results 'The tumoral fraction limit of detection' (page 11), Methods 'Evaluation metrics and missing values' (pages 26-27), Supplementary Table 2D Version: bioRxiv preprint version 1, posted 2025-11-27; not peer reviewed | not individually reviewed No individual claim review recorded Audit detailsField: Source artifact SHA-256: Hash scope: Not reproducible by re-download: bioRxiv rewrites the PDF on each download (ModDate and XMP dates set to the download time). A copy retrieved 2026-10-09T20:21:09Z has the same length (7,728,127 bytes) and SHA-256 fa7bcf8c25532f86dc99ed7d76a13a49ae70e29ab9f46559b3e0972e86aa9b96; resetting its three date stamps to any time on that day does not give the pinned hash, so another per-download field also differs. No result value is taken from this PDF. |
| description Descriptive fact transcribed from the pinned source. Context-only references | A benchmark of DNA methylation deconvolution methods for tumoral fraction estimation using DecoNFlow Preprint Results 'The tumoral fraction limit of detection' (page 11), Methods 'Evaluation metrics and missing values' (pages 26-27), Supplementary Table 2D Version: bioRxiv preprint version 1, posted 2025-11-27; not peer reviewed | not individually reviewed No individual claim review recorded Audit detailsField: Source artifact SHA-256: Hash scope: Not reproducible by re-download: bioRxiv rewrites the PDF on each download (ModDate and XMP dates set to the download time). A copy retrieved 2026-10-09T20:21:09Z has the same length (7,728,127 bytes) and SHA-256 fa7bcf8c25532f86dc99ed7d76a13a49ae70e29ab9f46559b3e0972e86aa9b96; resetting its three date stamps to any time on that day does not give the pinned hash, so another per-download field also differs. No result value is taken from this PDF. |
| Relationship: subject ctdnameth-20261009-protocol-giuili2025-wgbs-tt-tumour-fraction-lod Context-only references | A benchmark of DNA methylation deconvolution methods for tumoral fraction estimation using DecoNFlow Preprint Results 'The tumoral fraction limit of detection' (page 11), Methods 'Evaluation metrics and missing values' (pages 26-27), Supplementary Table 2D Version: bioRxiv preprint version 1, posted 2025-11-27; not peer reviewed | not individually reviewed No individual claim review recorded Audit detailsField: Source artifact SHA-256: Hash scope: Not reproducible by re-download: bioRxiv rewrites the PDF on each download (ModDate and XMP dates set to the download time). A copy retrieved 2026-10-09T20:21:09Z has the same length (7,728,127 bytes) and SHA-256 fa7bcf8c25532f86dc99ed7d76a13a49ae70e29ab9f46559b3e0972e86aa9b96; resetting its three date stamps to any time on that day does not give the pinned hash, so another per-download field also differs. No result value is taken from this PDF. |
| name metric_definition: ctdnameth-20261009-protocol-giuili2025-wgbs-tt-tumour-fraction-lod Context-only references | A benchmark of DNA methylation deconvolution methods for tumoral fraction estimation using DecoNFlow Preprint Results 'The tumoral fraction limit of detection' (page 11), Methods 'Evaluation metrics and missing values' (pages 26-27), Supplementary Table 2D Version: bioRxiv preprint version 1, posted 2025-11-27; not peer reviewed | not individually reviewed No individual claim review recorded Audit detailsField: Source artifact SHA-256: Hash scope: Not reproducible by re-download: bioRxiv rewrites the PDF on each download (ModDate and XMP dates set to the download time). A copy retrieved 2026-10-09T20:21:09Z has the same length (7,728,127 bytes) and SHA-256 fa7bcf8c25532f86dc99ed7d76a13a49ae70e29ab9f46559b3e0972e86aa9b96; resetting its three date stamps to any time on that day does not give the pinned hash, so another per-download field also differs. No result value is taken from this PDF. |
Sources and history
Release 2026-10-10-5bcb3ccc9543 · Record review: source checked
1 source records and release history
- A benchmark of DNA methylation deconvolution methods for tumoral fraction estimation using DecoNFlow · Original source · bioRxiv preprint version 1, posted 2025-11-27; not peer reviewed
Technical metadata and extraction receipts
Stable ID: ctdnameth-20261009-claim-giuili2025-lod-definition
- field
- metric_definition
- value
- Lowest tumour fraction at which the estimated fractions of the ten replicates are significantly higher than those of 0% tumour samples (one-tailed unpaired Mann-Whitney U test, Benjamini-Hochberg adjusted p < 0.01), moving from higher to lower fractions. Tested grid (Supplementary Table 2D): 0.0001, 0.001, 0.003, 0.007, 0.01, 0.025, 0.05, 0.1, 0.25, 0.5.
- source locator
- Preprint Results 'The tumoral fraction limit of detection' (page 11), Methods 'Evaluation metrics and missing values' (pages 26-27), Supplementary Table 2D
- review
- method: ai-assisted-source-review; method note: Compared with the Results LoD paragraph and Methods 'Evaluation metrics' in the text layer of a fresh copy of the PDF (the pinned PDF hash is not reproducible; see the source's hash_scope), and the tested grid with Supplementary Table 2D (media-4.xlsx, SHA-256 7057389b1ca89f5cd59b4004b7c8b00578988311b02bc5c9c5b7993915b4c06c, read for this review only).; reviewer: claude; reviewer note: Separate Claude review agent, independent of the extractor; no human review claimed; date: 2026-10-09; artifact sha256: fa7bcf8c25532f86dc99ed7d76a13a49ae70e29ab9f46559b3e0972e86aa9b96; retrieval url: https://www.biorxiv.org/content/10.1101/2025.11.27.688590v1.full.pdf; note: Text matches the cited paragraphs. Descriptive claim; no value or execution.